Pre*dis`po*si"tion (?), n.[Pref. pre- + disposition: cf. F. prédisposition.] 1. The act of predisposing, or the state of being predisposed; previous inclination, tendency, or propensity; predilection; -- applied to the mind; as, a predisposition to anger.

2. Previous fitness or adaptation to any change, impression, or purpose; susceptibility; -- applied to material things; as, the predisposition of the body to disease.