Ma*nip"u*late (?), v. t. [imp. & p. p. Manipulated (?); p. pr. & vb. n. Manipulating (?).] [LL. manipulatus, p. p. of manipulare to lead by the hand, fr. L. manipulus. See Maniple.] 1. To treat, work, or operate with the hands, especially when knowledge and dexterity are required; to manage in hand work; to handle; as, to manipulate scientific apparatus.

2. To control the action of, by management; as, to manipulate a convention of delegates; to manipulate the stock market; also, to manage artfully or fraudulently; as, to manipulate accounts, or election returns.

Ma*nip"u*late, v. i. To use the hands in dexterous operations; to do hand work; specifically, to manage the apparatus or instruments used in scientific work, or in artistic or mechanical processes; also, specifically, to use the hand in mesmeric operations.

• To move, arrange or operate something using the hands
  
• To influence, manage, direct, control or tamper with something to one's own advantage
  
• (medicine) To handle and move a body part, either as an examination or for a therapeutic purpose