An`tioch (23), an ancient capital of Syria, on the Orontes, called the Queen of the East, lying on the high-road between the E. and the W., and accordingly a busy centre of trade; once a city of great splendour and extent, and famous in the early history of the Church as the seat of several ecclesiastical councils and the birthplace of Chrysostom. There was an Antioch in Pisidia, afterwards called Cæsarea.